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thin-walled box continuous girder with variable cross-sections in considering effect of large deflection and shearlag

Yuji CHEN, Qizhi LUO,

《结构与土木工程前沿(英文)》 2009年 第3卷 第4期   页码 352-356 doi: 10.1007/s11709-009-0057-7

摘要: In order to study the mechanics behavior of a thin-walled box continuous girder with variable cross-sections, using potential variation theories, considering the effect of shear lag of flange’s stress and the nonlinear geometry of vertical displacement, and evolving five generalized displacements with the spline function, the large deflection problem of the thin-walled box continuous girder with variable cross-section was transformed to a nonlinear algebraic equation, which was solved using the Newton-Raphon iterative method. The results of the calculation show that different shear lag warp functions to the cantilever, top and bottom plate should be taken to analyze the mechanics behavior of the thin-walled box continuous girder reliably. The thin-walled box continuous girder with variable cross-sections has more reasonable stress state and is more adaptable for the longitudinal change of internal forces than that with equal cross-sections. The effect of large deflection on the stress and displacement of the thin-walled box continuous girder with variable cross-sections depends on the values of the load.

关键词: thin-walled box girder with variable cross-sections     potential variational theory     shear lag     large deflection problem    

CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells

null

《医学前沿(英文)》 2017年 第11卷 第4期   页码 554-562 doi: 10.1007/s11684-017-0543-6

摘要:

T cells engineered with chimeric antigen receptor (CAR) have been successfully applied to treat advanced refractory B cell malignancy. However, many challenges remain in extending its application toward the treatment of solid tumors. The immunosuppressive nature of tumor microenvironment is considered one of the key factors limiting CAR-T efficacy. One negative regulator of T cell activity is lymphocyte activation gene-3 (LAG-3). We successfully generated LAG-3 knockout T and CAR-T cells with high efficiency using CRISPR-Cas9 mediated gene editing and found that the viability and immune phenotype were not dramatically changed during in vitro culture. LAG-3 knockout CAR-T cells displayed robust antigen-specific antitumor activity in cell culture and in murine xenograft model, which is comparable to standard CAR-T cells. Our study demonstrates an efficient approach to silence immune checkpoint in CAR-T cells via gene editing.

关键词: CAR-T     CRISPR-Cas9     LAG-3    

Dynamic behavior of superheated steam and ways of control

LI Xu

《能源前沿(英文)》 2008年 第2卷 第1期   页码 25-30 doi: 10.1007/s11708-008-0014-5

摘要: A simple way of calculating the dynamic behavior of a superheater is presented. A comparison of the measured data with the calculated result verifies the accuracy of this simple method. It is the first time that a phase compensation for real roots, i.e., the twin lead/lag loop which is facile for engineering applications, is used in superheated steam temperature control. Numerous simulation results show that both the response time lapse and maximal dynamic deviation are greatly reduced. Moreover, a formula to calculate the setting parameters is presented, together with a practical example of its engineering application in superheated steam temperature control with single-stage attemperation in a power plant boiler. This method can remarkably improve the control performance of superheated steam temperature and makes it possible for one stage attemperation to be sufficient for the superheater of power plant boilers, thus simplifying the superheater system and reducing investment. Because the control performance is remarkably raised, the set values of the steam temperature control system can be raised above rated values and also the operational economy, without impairing the operation safety.

关键词: engineering     investment     Numerous simulation     lead/lag     temperature    

Modeling of shear walls using finite shear connector elements based on continuum plasticity

Ulf Arne GIRHAMMAR, Per Johan GUSTAFSSON, Bo KÄLLSNER

《结构与土木工程前沿(英文)》 2017年 第11卷 第2期   页码 143-157 doi: 10.1007/s11709-016-0377-3

摘要: Light-frame timber buildings are often stabilized against lateral loads by using diaphragm action of roofs, floors and walls. The mechanical behavior of the sheathing-to-framing joints has a significant impact on the structural performance of shear walls. Most sheathing-to-framing joints show nonlinear load-displacement characteristics with plastic behavior. This paper is focused on the finite element modeling of shear walls. The purpose is to present a new shear connector element based on the theory of continuum plasticity. The incremental load-displacement relationship is derived based on the elastic-plastic stiffness tensor including the elastic stiffness tensor, the plastic modulus, a function representing the yield criterion and a hardening rule, and function representing the plastic potential. The plastic properties are determined from experimental results obtained from testing actual connections. Load-displacement curves for shear walls are calculated using the shear connector model and they are compared with experimental and other computational results. Also, the ultimate horizontal load-carrying capacity is compared to results obtained by an analytical plastic design method. Good agreements are found.

关键词: shear walls     wall diaphragms     finite element modelling     plastic shear connector     analytical modelling     experimental comparison    

Nonlinear numerical simulation of punching shear behavior of reinforced concrete flat slabs with shear-heads

Dan V. BOMPA, Ahmed Y. ELGHAZOULI

《结构与土木工程前沿(英文)》 2020年 第14卷 第2期   页码 331-356 doi: 10.1007/s11709-019-0596-5

摘要: This paper examines the structural response of reinforced concrete flat slabs, provided with fully-embedded shear-heads, through detailed three-dimensional nonlinear numerical simulations and parametric assessments using concrete damage plasticity models. Validations of the adopted nonlinear finite element procedures are carried out against experimental results from three test series. After gaining confidence in the ability of the numerical models to predict closely the full inelastic response and failure modes, numerical investigations are carried out in order to examine the influence of key material and geometric parameters. The results of these numerical assessments enable the identification of three modes of failure as a function of the interaction between the shear-head and surrounding concrete. Based on the findings, coupled with results from previous studies, analytical models are proposed for predicting the rotational response as well as the ultimate strength of such slab systems. Practical recommendations are also provided for the design of shear-heads in RC slabs, including the embedment length and section size. The analytical expressions proposed in this paper, based on a wide-ranging parametric assessment, are shown to offer a more reliable design approach in comparison with existing methods for all types of shear-heads, and are suitable for direct practical application.

关键词: non-linear numerical modelling     concrete damage plasticity     RC flat slabs     shear-heads     punching shear    

Behaviour of self-centring shear walls——A state of the art review

《结构与土木工程前沿(英文)》 2023年 第17卷 第1期   页码 53-77 doi: 10.1007/s11709-022-0850-0

摘要: The application of unbonded post-tensioning (PT) in structural walls has led to the development of advanced self-centring (rocking) shear wall systems that has significant advantages, including accelerated construction due to the incorporation of prefabricated elements and segmental construction for different materials (e.g., concrete, masonry, and timber), reduced residual drifts, and little damage upon extreme seismic and wind loads. Concrete, masonry, and timber are often used for the construction of unbonded PT structural wall systems. Despite extensive research since the 1980s, there are no well-established design guidelines available on the shear wall configuration with the required energy dissipation system, joint’s locations and acceptance criteria for shear sliding, confinement, seismic performance factors, PT loss, PT force range and residual drifts of shear walls subjected to lateral loads. In this research a comprehensive state-of-the-art literature review was performed on self-centring shear wall system. An extensive study was carried out to collect a database of 100 concrete, masonry, and self-centring shear wall tests from the literature. The established database was then used to review shear walls’ configurations, material, and components to benchmark requirements applicable for design purposes. The behaviour of concrete, masonry and timber shear walls were compared and critically analysed. The general behaviour, force-displacement performance of the walls, ductility, and seismic response factors, were critically reviewed and analysed for different self-centring wall systems to understand the effect of different parameters including configurations of the walls, material used for construction of the wall (concrete, masonry, timber) and axial stress ratio. The outcome of this research can be used to better understand the behaviour of self-centring wall system in order to develop design guidelines for such walls.

关键词: self-centring shear walls     rocking walls     energy dissipation     seismic performance factors     PT loss     residual drift    

Prediction of the shear wave velocity

Amoroso SARA

《结构与土木工程前沿(英文)》 2014年 第8卷 第1期   页码 83-92 doi: 10.1007/s11709-013-0234-6

摘要: The paper examines the correlations to obtain rough estimates of the shear wave velocity from non-seismic dilatometer tests (DMT) and cone penetration tests (CPT). While the direct measurement of is obviously preferable, these correlations may turn out useful in various circumstances. The experimental results at six international research sites suggest that the DMT predictions of from the parameters (material index), (horizontal stress index), (constrained modulus) are more reliable and consistent than the CPT predictions from (cone resistance), presumably because of the availability, by DMT, of the stress history index .

关键词: horizontal stress index     shear wave velocity     flat dilatometer test     cone penetration test    

On braced trapezoidal corrugated steel shear panels: An experimental and numerical study

《结构与土木工程前沿(英文)》 2023年 第17卷 第3期   页码 396-410 doi: 10.1007/s11709-023-0934-5

摘要: In this study, a new system consisting of a combination of braces and steel infill panels called the braced corrugated steel shear panel (BCSSP) is presented. To obtain the hysteretic behavior of the proposed system, the quasi-static cyclic performances of two experimental specimens were first evaluated. The finite element modeling method was then verified based on the obtained experimental results. Additional numerical evaluations were carried out to investigate the effects of different parameters on the system. Subsequently, a relationship was established to estimate the buckling shear strength of the system without considering residual stresses. The results obtained from the parametric study indicate that the corrugated steel shear panel (CSSP) with the specifications of a = 30 mm, t = 2 mm, and θ = 90° had the highest energy dissipation capacity and ultimate strength while the CSSP with the specifications of a = 30 mm, t = 2 mm, and θ = 30° had the highest initial stiffness. It can thus be concluded that the latter CSSP has the best structural performance and that increasing the number of corrugations, corrugation angle, and plate thickness and decreasing the sub-panel width generally enhance the performance of CSSPs in terms of the stability of their hysteretic behaviors.

关键词: trapezoidal corrugated plate     steel shear panel     braced steel shear panel     experimental study     buckling resistance.    

Experimental study on shear behavior of reinforced concrete beams with web horizontal reinforcement

Dong XU,Yu ZHAO,Chao LIU

《结构与土木工程前沿(英文)》 2014年 第8卷 第4期   页码 325-336 doi: 10.1007/s11709-014-0080-1

摘要: In determining the shear capacity of reinforced concrete beams, current codes do not provide any calculation method to evaluate the influence of web horizontal reinforcement, although they exist as structural reinforcements (or skin reinforcement). The present paper comprises results of 11 reinforced concrete beams in an effort to investigate the influence of web horizontal reinforcement on the shear behavior of reinforced concrete beams. The primary design variables are the shear-span-depth ratio, different reinforcement ratio of stirrups and web horizontal reinforcement. Influence of web horizontal reinforcement on crack patterns and failure mode was studied. It was found that web horizontal reinforcement can increase the shear capacity of the beams and restrain growth of inclined cracks effectively. Test results are very valuable, as very few references of shear tests can be found focusing on the effect of web horizontal reinforcement on the shear capacity of the beams.

关键词: reinforced concrete beam     shear strength     web horizontal reinforcement     experiments    

变距/摆振耦合对直升机空中共振稳定性的影响

薛海峰,向锦武,张晓谷,李书强

《中国工程科学》 2007年 第9卷 第9期   页码 58-62

摘要:

采用多桨叶坐标转换和复数坐标 变换等方法,研究了变距/摆振耦合对直升 机空中共振的影响;推导出完全引入变距/ 摆振耦合的直升机空中共振分析公式,建立 了相应的分析模型和计算程序。利用系统的 特征值研究了直升机空中共振的动不稳定性, 得出变距/摆振耦合对直升机空中共振的影响 ;通过系统的特征向量与各自由度之间的相互 作用(能量关系)的研究,揭示了空中共振机理 ,以某型直升机为例进行了计算分析。研究表明 :正的变距/摆振耦合可以抑制旋翼/机体耦合 系统的动不稳定性,在同时存在挥舞/摆振耦合 和正的变距/摆振耦合时,直升机的旋翼/机体 耦合系统为绝对稳定。

关键词: 直升机     动不稳定性     直升机空中共振     变距/摆振耦合    

Effect of loading rate on shear strength parameters of mechanically and biologically treated waste

《环境科学与工程前沿(英文)》 2022年 第16卷 第12期 doi: 10.1007/s11783-022-1595-7

摘要:

● Mechanical behavior of MBT waste affected by loading rate was investigated.

关键词: Mechanically and biologically treated waste     Landfill     Triaxial test     Loading rate     Axial strain     Shear strength parameter    

Micromixing performance of the teethed high shear mixer under semi-batch operation

《化学科学与工程前沿(英文)》 2022年 第16卷 第4期   页码 546-559 doi: 10.1007/s11705-021-2069-3

摘要: Semi-batch operated reaction processes are necessary for some competitive reaction systems to achieve a desirable process selectivity and productivity of fine chemical products. Herein the structural and operating parameters of the teethed high shear mixers were adjusted to study the micromixing performance in the semi-batch operated system, using the Villermaux/Dushman reaction system. The results indicate that the rising of the rotor speed and the number of rotor teeth, the decrease of the width of the shear gap and the radial distance between the feed position and the inner wall of stator can enhance the micromixing level and lead to the decrease of the segregation index. Additionally, computational fluid dynamics calculations were carried out to disclose the evolution of the flow pattern and turbulent energy dissipation rate of the semi-batch operated high shear mixer. Furthermore, the correlation was established with a mean relative error of 8.05% and R2 of 0.955 to fit the segregation index and the parameters studied in this work, which can provide valuable guidance on the design and optimization of the semi-batch operated high shear mixers in practical applications.

关键词: high shear mixer     semi-batch operation     micromixing performance     Villermaux/Dushman system     segregation index    

Predicting the capacity of perfobond rib shear connector using an ANN model and GSA method

Guorui SUN; Jun SHI; Yuang DENG

《结构与土木工程前沿(英文)》 2022年 第16卷 第10期   页码 1233-1248 doi: 10.1007/s11709-022-0878-1

摘要: Due to recent advances in the field of artificial neural networks (ANN) and the global sensitivity analysis (GSA) method, the application of these techniques in structural analysis has become feasible. A connector is an important part of a composite beam, and its shear strength can have a significant impact on structural design. In this paper, the shear performance of perfobond rib shear connectors (PRSCs) is predicted based on the back propagation (BP) ANN model, the Genetic Algorithm (GA) method and GSA method. A database was created using push-out test test and related references, where the input variables were based on different empirical formulas and the output variables were the corresponding shear strengths. The results predicted by the ANN models and empirical equations were compared, and the factors affecting shear strength were examined by the GSA method. The results show that the use of ANN model optimization by GA method has fewer errors compared to the empirical equations. Furthermore, penetrating reinforcement has the greatest sensitivity to shear performance, while the bonding force between steel plate and concrete has the least sensitivity to shear strength.

关键词: perfobond rib shear connector     shear strength     ANN model     global sensitivity analysis    

Uncertainty of concrete strength in shear and flexural behavior of beams using lattice modeling

《结构与土木工程前沿(英文)》 2023年 第17卷 第2期   页码 306-325 doi: 10.1007/s11709-022-0890-5

摘要: This paper numerically studied the effect of uncertainty and random distribution of concrete strength in beams failing in shear and flexure using lattice modeling, which is suitable for statistical analysis. The independent variables of this study included the level of strength reduction and the number of members with reduced strength. Three levels of material deficiency (i.e., 10%, 20%, 30%) were randomly introduced to 5%, 10%, 15%, and 20% of members. To provide a database and reliable results, 1000 analyses were carried out (a total of 24000 analyses) using the MATLAB software for each combination. Comparative studies were conducted for both shear- and flexure-deficit beams under four-point loading and results were compared using finite element software where relevant. Capability of lattice modeling was highlighted as an efficient tool to account for uncertainty in statistical studies. Results showed that the number of deficient members had a more significant effect on beam capacity compared to the level of strength deficiency. The scatter of random load-capacities was higher in flexure (range: 0.680–0.990) than that of shear (range: 0.795–0.996). Finally, nonlinear regression relationships were established with coefficient of correlation values (R2) above 0.90, which captured the overall load–deflection response and level of load reduction.

关键词: lattice modeling     shear failure     flexural failure     uncertainty     deficiency     numerical simulation    

Fatigue shear performance of concrete beams reinforced with hybrid (glass-fiber-reinforced polymer+ steel

《结构与土木工程前沿(英文)》 2021年 第15卷 第3期   页码 576-594 doi: 10.1007/s11709-021-0728-6

摘要: Reinforced concrete beams consisting of both steel and glass-fiber-reinforced polymer rebars exhibit excellent strength, serviceability, and durability. However, the fatigue shear performance of such beams is unclear. Therefore, beams with hybrid longitudinal bars and hybrid stirrups were designed, and fatigue shear tests were performed. For specimens that failed by fatigue shear, all the glass-fiber-reinforced polymer stirrups and some steel stirrups fractured at the critical diagonal crack. For the specimen that failed by the static test after 8 million fatigue cycles, the static capacity after fatigue did not significantly decrease compared with the calculated value. The initial fatigue level has a greater influence on the crack development and fatigue life than the fatigue level in the later phase. The fatigue strength of the glass-fiber-reinforced polymer stirrups in the specimens was considerably lower than that of the axial tension tests on the glass-fiber-reinforced polymer bar in air and beam-hinge tests on the glass-fiber-reinforced polymer bar, and the failure modes were different. Glass-fiber-reinforced polymer stirrups were subjected to fatigue tension and shear, and failed owing to shear.

关键词: fatigue     shear     hybrid stirrups     hybrid reinforcement     fiber-reinforced polymer    

标题 作者 时间 类型 操作

thin-walled box continuous girder with variable cross-sections in considering effect of large deflection and shearlag

Yuji CHEN, Qizhi LUO,

期刊论文

CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells

null

期刊论文

Dynamic behavior of superheated steam and ways of control

LI Xu

期刊论文

Modeling of shear walls using finite shear connector elements based on continuum plasticity

Ulf Arne GIRHAMMAR, Per Johan GUSTAFSSON, Bo KÄLLSNER

期刊论文

Nonlinear numerical simulation of punching shear behavior of reinforced concrete flat slabs with shear-heads

Dan V. BOMPA, Ahmed Y. ELGHAZOULI

期刊论文

Behaviour of self-centring shear walls——A state of the art review

期刊论文

Prediction of the shear wave velocity

Amoroso SARA

期刊论文

On braced trapezoidal corrugated steel shear panels: An experimental and numerical study

期刊论文

Experimental study on shear behavior of reinforced concrete beams with web horizontal reinforcement

Dong XU,Yu ZHAO,Chao LIU

期刊论文

变距/摆振耦合对直升机空中共振稳定性的影响

薛海峰,向锦武,张晓谷,李书强

期刊论文

Effect of loading rate on shear strength parameters of mechanically and biologically treated waste

期刊论文

Micromixing performance of the teethed high shear mixer under semi-batch operation

期刊论文

Predicting the capacity of perfobond rib shear connector using an ANN model and GSA method

Guorui SUN; Jun SHI; Yuang DENG

期刊论文

Uncertainty of concrete strength in shear and flexural behavior of beams using lattice modeling

期刊论文

Fatigue shear performance of concrete beams reinforced with hybrid (glass-fiber-reinforced polymer+ steel

期刊论文